Fear of Public Speaking & Genetics

How it works 

When the brain senses a threat in the environment, a part of the brain called the amygdala responds by activating the “fight or flight” response. This response includes many biological changes, like a faster heart rate and increased blood flow to the brain. Studies have found that when speaking in front of others, people with a fear of public speaking may have more active amygdalas.

The genetics behind the fear of public speaking

23andMe researchers identified 802 genetic markers that are associated with having a fear of public speaking. In addition to genetics, other factors like age, sex, and ancestry can also influence one’s chances of having a fear of public speaking.  

Did you know? 

For those with a fear of public speaking, preparation and practice can help. Some people may benefit from talking to a healthcare professional.

Explore more

Want to learn more? 23andMe’s Health + Ancestry Service can give you a closer look at the genetic variants that affect the fear of public speaking. Order now and you’ll receive 150+ personalized reports with insights on your health, wellness, traits and more.

References

Furlotte NA et al. (2015). “23andMe White Paper 23-12: Estimating complex phenotype prevalence using predictive models.” 23andMe White Paper 23-12.

Kozlowska K et al. (2015). “Fear and the Defense Cascade: Clinical Implications and Management.” Harv Rev Psychiatry. 23(4):263-87.

Mayo Clinic (2017, May 17). “Fear of public speaking: how can I overcome it?” Retrieved May 23, 2019, from https://www.mayoclinic.org/diseases-conditions/specific-phobias/expert-answers/fear-of-public-speaking/faq-20058416

Rodrigues SM et al. (2009). “The influence of stress hormones on fear circuitry.” Annu Rev Neurosci. 32:289-313.

Shin LM et al. (2010). “The neurocircuitry of fear, stress, and anxiety disorders.” Neuropsychopharmacology. 35(1):169-91.

Tillfors M et al. (2001). “Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study.” Am J Psychiatry. 158(8):1220-6.